How to use MSM
The daily dose range from 2 to 30 grams, depending on one's diet, body weight, condition of health, etc. The precise dose is not critical as MSM is considered food and not a medicine. The first week or two larger doses can be taken to compensate a deficiency.

It is known that some forms of minerals, particularly inorganic minerals, are poorly absorbed. The organic sulfur in MSM is extremely well absorbed.
Administered orally, a portion of MSM binds to the mucosal membrane
receptor sites, the rest is very fast absorbed into the bloodstream. Within 24 hours of administration, the sulfur derived from MSM can be found in liver, kidneys and blood.

Destoxification
For those who have arthritis or other similar degenerative condition, fibromyalgia, asthma, digestive disorders including parasites, or other health problems, it is best to detoxify first the system using higher doses of MSM to obtain faster results. Lungs, considered one of the vital organs of the body, respond much faster than arthritic joints. One can notice a difference in one's lungs within 3 days, while other conditions such as arthritis will probably take 2-3 weeks to see improvement. The longer it is used, the better the results. The higher the amount used, the faster the result.

First Week
Detoxification with 20-30 grams MSM daily. Dissolve 1/2 teaspoon of (aprox. 2,5gr) MSM into 1/4 liter of water. There is little taste. Drink at least eight 1/4 liter glasses of MSM water daily, spread throughout the day before 18.00. This is a total of 20 gr MSM. 

Twice a day, first in the morning and again in the afternoon, add a mineral supplement to the water. This is needed to heal tissues. Especially important are potassium, zinc, manganese, and calcium ascorbate (Vitamin C) and B vitamins.

Water is important to flush toxins out of the body. More water, the faster the results, and the fewer side effects will be experienced from the detoxification process.

Possible negative side effects: Headaches and fatigue for the first few days due to the detoxification process. If this occurs, drink more water. Do not be alarmed as this is part of the natural healing process.

Second Week
Take 10-20 grams MSM daily. Drink at least four 1/4 liter glasses of MSM water daily. Twice daily, add a mineral supplement to the water.

For therapeutic maintenance take 2-10 grams MSM daily. (1 teaspoon = 4 gr) 

NOTE
Some authorities express that sulfur is more effective when taken with Vitamin C, B Complex vitamins, especially B-1, B-5 and biotin and electrolytes. 
MSM is rated as one of the least toxic substances in biology, similar to water. 
If one takes more MSM than needed, it simply passes through the body and
is excreted in the urine. The excess of MSM won't harm. MSM has been widely tested as a food ingredient without any reports of allergic reactions.